Kagame may refer to:
- Paul Kagame (b. 1957), President of Rwanda
- Alexis Kagame (1912-1981), Rwandan historian
- Jeannette Kagame (b. 1961), First Lady of Rwanda
- Kagame Inter-Club Cup, a football club competition also known as the CECAFA Club Cup
- 2008 Kagame Inter-Club Cup
- 2009 Kagame Inter-Club Cup