International Nonproprietary Name - Name Stems

Name Stems

Drugs from the same therapeutic or chemical class are usually given names with the same stem. Stems are mostly placed word-finally, but in some cases word-initial stems are used. They are collected in a publication informally known as the Stem Book.

Examples are:

  • -coxib for COX-2 inhibitors, a type of anti-inflammatory drugs (e.g. celecoxib)
  • -mab for monoclonal antibodies (e.g. infliximab); see Nomenclature of monoclonal antibodies
  • -olol for beta blockers (e.g. atenolol)
  • -oxetine for fluoxetine derivatives, a group of antidepressants
  • -pril for ACE inhibitors (e.g. captopril)
  • -vastatin for HMG-CoA reductase inhibitors, a group of cholesterol lowering agents (e.g. simvastatin)
  • io- for iodine containing radiopharmaceuticals (e.g. iobenguane)

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Famous quotes containing the word stems:

    “One who pressed forward incessantly and never rested from his labors, who grew fast and made infinite demands on life, would always find himself in a new country or wilderness, and surrounded by the raw material of life. He would be climbing over the prostrate stems of primitive forest-trees.”
    —Henry David Thoreau (1817–1862)

    “A passion for politics stems usually from an insatiable need, either for power, or for friendship and adulation, or a combination of both.”
    —Fawn M. Brodie (1915–1981)