Lung Cancer Concerns
On April 9, 2008, Pfizer announced in its "Dear Doctor" letter that Exubera may have been associated with lung cancer: of the 4,740 patients who used Exubera in clinical trials, six have developed lung cancer as of April 2008, compared to only one of the 4,292 patients in the placebo group. The association was not statistically significant, and Pfizer maintained in its letter that "Exubera remains a safe and effective medication."
In a letter 18 June 2008, Pfizer informed UK doctors of the above mentioned six cases, noting that they all had a prior history of cigarette smoking and that they were planning to investigate further the "observed imbalance in diagnosed lung cases" with an international observational trial. Pfizer's letter also stated that Nektar had stopped searching for a new marketing partner and therefore Pfizer would withdraw its Marketing Authorisation around September 2008.
Read more about this topic: Inhalable Insulin
Famous quotes containing the words lung cancer, lung, cancer and/or concerns:
“Dylan used to sound like a lung cancer victim singing Woody Guthrie. Now he sounds like a Rolling Stone singing Immanuel Kant.”
—Also quoted in Robert Shelton, No Direction Home, ch. 2, “Prophet Without Honor” (1986)
“Time is here and you’ll go his way.
Your lung is waiting in the death market.
Your face beside me will grow indifferent.
Darling, you will yield up your belly and be
cored like an apple.”
—Anne Sexton (1928–1974)
“The truth is that Mozart, Pascal, Boolean algebra, Shakespeare, parliamentary government, baroque churches, Newton, the emancipation of women, Kant, Marx, and Balanchine ballets don’t redeem what this particular civilization has wrought upon the world. The white race is the cancer of human history.”
—Susan Sontag (b. 1933)
“We do not marry for ourselves, whatever we say; we marry just as much or more for our posterity, for our family. The practice and benefit of marriage concerns our race very far beyond us.”
—Michel de Montaigne (1533–1592)