History
Both MRI and MRS are based on Nuclear Magnetic Resonance Spectroscopy (NMR), a technique used by chemists and physicists in the analysis and characterization of small molecules in solid, liquid, and gel-like solutions. Theoretically, MRS can be used to detect nuclei such as carbon (13C), nitrogen (15N), fluorine (19F), sodium (23Na), phosphorus (31P) and hydrogen (1H), however only the latter two are present in significant abundance to be detected in humans. Hydrogen is the most commonly detected nucleus due to its high natural abundance, acute sensitivity to magnetic manipulation, well known simple technique, and relatively easily discernible spectra.
Read more about this topic: In Vivo Magnetic Resonance Spectroscopy
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