Haemoglobin-based Oxygen Carriers - Military Use

Military Use

In the 1980s, an HBOC was developed by the US Army at the Letterman Army Institute of Research (LAIR) which did not need typing. However, in clinical trials the HBOC were proven to be problematic, with more deaths using the HBOC than in the control group. Yet, their use would be of value to sustain the wounded in military conflicts. PolyHeme is currently in field trials with the US Army. Experiments continue with requirements include long shelf-life, no need for refrigeration, and minimal side-effects.

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