Haemoglobin-based Oxygen Carriers
Hemoglobin-based oxygen carriers are one of two main types of oxygen-carrying blood substitutes in development, the other one being perfluorocarbon emulsions. As of 2011 there are no haemoglobin-based oxygen carriers or perfluorocarbon emulsions approved for commercial use in North America or Europe. The only countries where these products are approved for general use is South Africa and Russia.
This is because they significantly increase the risk of death and myocardial infarction. It has been recommended that further phase III trials not be conducted until these products are as effective as the current standard of care.
Optimism about near term approval of oxygen carriers has decreased recently due to poor result from a number of clinical trials.
Read more about Haemoglobin-based Oxygen Carriers: Classification, Safety, Military Use, History
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