Guanine Nucleotide Exchange Factor

Guanine Nucleotide Exchange Factor

Guanine nucleotide exchange factors (GEFs) activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP). A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity. Some GEFs can activate multiple GTPases while others are specific to a single GTPase.

Read more about Guanine Nucleotide Exchange Factor:  Function, Mechanism, Structure and Specificity, Regulation, GEFs and Cancer, Examples of GEFs

Famous quotes containing the words exchange and/or factor:

    Ideal conversation must be an exchange of thought, and not, as many of those who worry most about their shortcomings believe, an eloquent exhibition of wit or oratory.
    Emily Post (1873–1960)

    Weapons are an important factor in war, but not the decisive factor; it is people, not things, that are decisive. The contest of strength is not only a contest of military and economic power, but also a contest of human power and morale. Military and economic power is necessarily wielded by people.
    Mao Zedong (1893–1976)