Possible Glutamate Based Treatment
An early clinical trial by Eli Lilly of the drug LY2140023 has shown potential for treating schizophrenia without the weight gain and other side-effects associated with conventional anti-psychotics. This drug acts as a selective agonist at metabotropic mGluR2 and mGluR3 glutamate receptors (the mGluR3 gene has previously been associated with schizophrenia.).
Studies of glycine (and related co-agonists at the NMDA receptor) added to conventional anti-psychotics have also found some evidence that these may improve symptoms in schizophrenia.
Read more about this topic: Glutamate Hypothesis Of Schizophrenia
Famous quotes containing the words based and/or treatment:
“Captain, down where I come from we dearly love our whiskey, but we don’t drink with a man unless we respect him.”
—James Poe, U.S. screenwriter, and Based On Play. Robert Aldrich. Sergeant Tolliver (Buddy Ebsen)
“The treatment of African and African American culture in our education was no different from their treatment in Tarzan movies.”
—Ishmael Reed (b. 1938)