Layers
The GBM contains three layers:
| Layer | Location | Composition | Function |
| lamina rara externa | adjacent to podocyte processes | heparan sulfate | blocks by charge |
| lamina densa | dark central zone | type 4 collagen and laminin | blocks by size (Molecular Weight > 5800kDa) |
| lamina rara interna | adjacent to endothelial cells | heparan sulfate | blocks by charge |
Read more about this topic: Glomerular Basement Membrane
Famous quotes containing the word layers:
“I think it’s the real world. The people we’re writing about in professional sports, they’re suffering and living and dying and loving and trying to make their way through life just as the brick layers and politicians are.”
—Walter Wellesley (Red)
“The force of a death should be enormous but how can you know what kind of man you’ve killed or who was the braver and stronger if you have to peer through layers of glass that deliver the image but obscure the meaning of the act? War has a conscience or it’s ordinary murder.”
—Don Delillo (b. 1926)