Germain, the French variant of the name Germanus, may refer to:
People
- Sophie Germain, French mathematician
- Paul Germain, American animation producer
- George Germain, 1st Viscount Sackville, British Secretary of State during the American Revolutionary War
- Goermans, a harpsichord-making family
- Germain de Brie, French poet, writing in Latin
As a pseudonym
- "Mr. KABC", Marc Germain, a radio talk show host in Los Angeles, California
- Ernest Mandel, pseudonym for a Trotskyist politician
In sports and entertainment
- Germain Arena, an arena in Naples, Florida
- Germain Racing, a NASCAR racing team
- Germain Amphitheater, a concert venue in Columbus, Ohio
In business
- Germain, a pioneer Belgian carmaker