Fsh-receptor

FSH-receptor

Identifiers Symbols FSHR; FSHRO; LGR1; ODG1 External IDs OMIM: 136435 MGI: 95583 HomoloGene: 117 IUPHAR: FSH receptor ChEMBL: 2024 GeneCards: FSHR Gene

Gene Ontology
Molecular function	• follicle-stimulating hormone receptor activity • protein binding • peptide hormone binding
Cellular component	• endosome • plasma membrane • cell surface • integral to membrane
Biological process	• G-protein coupled receptor signaling pathway • adenylate cyclase-activating G-protein coupled receptor signaling pathway • spermatogenesis • female gamete generation • gonad development • male gonad development • female gonad development • regulation of chromosome organization • spermatogenesis, exchange of chromosomal proteins • transcytosis
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2492 14309 Ensembl ENSG00000170820 ENSMUSG00000032937 UniProt P23945 P35378 RefSeq (mRNA) NM_000145.3 NM_013523.3 RefSeq (protein) NP_000136.2 NP_038551.3 Location (UCSC) Chr 2:
49.19 – 49.38 Mb Chr 17:
88.99 – 89.2 Mb PubMed search

The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). Its activation is necessary for the hormonal functioning of FSH. FSHRs are found in the ovary, testis, and uterus.