Food Intolerance - Research Directions

Research Directions

A Low FODMAP diet now has an evidence base sufficiently strong to recommend its widespread application in conditions such as IBS and IBD. Restriction of Fermentable Oligo-, Di- and Mono- saccharides and Polyols globally, rather than individually, controls the symptoms of functional gut disorders (e.g. IBS), and the majority of IBD patients respond just as well. It is more successful than restricting only Fructose and Fructans, which are also FODMAPs, as is recommended for those with Fructose malabsorption. Longer term compliance with the diet was high.

A randomised controlled trial on IBS patients found relaxing an IgG-mediated food intolerance diet led to a 24% greater deterioration in symptoms compared to those on the elimination diet and concluded food elimination based on IgG antibodies may be effective in reducing IBS symptoms and is worthy of further biomedical research.

Intestinal or bowel hyperpermeability, so called leaky gut, has been linked to food allergies and some food intolerances. Research is currently focussing on specific conditions and effects of certain food constituents. At present there are a number of ways to limit the increased permeability, but additional studies are required to assess if this approach reduces the prevalence and severity of specific conditions.

Read more about this topic:  Food Intolerance

Famous quotes containing the words research and/or directions:

    The great question that has never been answered, and which I have not yet been able to answer, despite my thirty years of research into the feminine soul, is “What does a woman want?”
    Sigmund Freud (1856–1939)

    My friend devotes himself to his life, whenever he can find the spare time. His motto is: ‘Don’t just sit there: live!’ So he’s too busy to stand, to walk, to do anything, except to live. He even refused to kiss a girl, when invited, on the grounds that it was time again to be living. Schedules are sacred to him.
    Marvin Cohen, U.S. author and humorist. The Self-Devoted Friend, New Directions (1967)