FACS may refer to:
- Fluorescence-activated cell sorting, a biophysical technique used in flow cytometry.
- Facial Action Coding System, a procedure to systematically describe human facial expressions.
- Family and consumer science
- Fellow of the American College of Surgeons
- Field Automated Communication System
- First Assembly Christian School, Memphis, Tennessee
- Formal Aspects of Computing Science, a British Computer Society Specialist Group
- Families and Children Study, a longitudinal study in Great Britain
- Flexible Assembly Configuration System, a software solution for automated assembly line
- Fair Access to Care Services, UK Social Services regulation