Enterocytozoon Bieneusi - Abstract

Abstract

Enterocytozoon bieneusi, commonly known as microsporidia, is a unicellular, obligate intracellular eukaryote. Their life cycle includes a proliferative merogonic stage, followed by a sporogonic stage resulting in small, environmentally resistant, infective spores, which is their transmission mode. The spores contain a long, coiled polar tube, which distinguishes them from all other organisms and has a crucial role in host cell invasion. E. bieneusi was first found in an AIDS patient in France in 1985 and was later found in swine in 1996 in fecal samples. It causes diarrhea thus the pigs excrete more spores spreading the disease. As this pathogen is very prevalent throughout the world, E. bieneusi is found in a wide variety of hosts including pigs, humans, and other mammals. E. bieneusi can be studied using TEM, light microscopy, PCR and immunofluorescence and can be cultured for short-term. It has not been known yet whether the pathogen gets any diseases and there seem to be widespread economic implications of this pathogen in the swine industry. Furthermore, several treatment medications such as Fumagilin and albendazole seem promising (Mathis et al. 2005).