Eli or ELI may refer to:
- El (deity), or Eli, a variant on the name of God as spoken in Arabic, Hebrew, and Aramaic
- Eli (name), a common first name in Hebrew (includes a list of people and fictional characters with the given name Eli)
- Eli (Bible), Biblical priest of Shiloh and Israelite judge
- Eli, a nickname for a Yale University student or graduate, after Yale benefactor Elihu Yale
- Eli, Mateh Binyamin, an Israeli settlement in the West Bank
- Éli, a medieval kingdom in Ireland
- Environmental Law Institute, legal resource for environmental law issues
- Extreme Light Infrastructure, a proposed high energy laser research facility of the European Union
- ELI (film), a 2007 short science-fiction thriller
- Eli (Jan Akkerman album),
- Eli (Supernaut album), 2006
- E.L.I. (Ice Prince album), 2011
- Eli (Xena), a fictional character from the television series Xena: Warrior Princess
- ELI an acronym for Earth Learning Idea, see Earthlearningidea (ELI)