EFC may stand for:
- Earth: Final Conflict, a science fiction television series
- EFC,Egg Farmers of Canada, a Canadian national organization
- Electronic Frontier Canada, a Canadian civil rights organization
- Elite Fighting Championship, a Canadian mixed martial arts competition
- Elizabeth Finn Care, a British grant-giving charity
- Emergency Fleet Corporation (aka United States Shipping Board Merchant Fleet Corporation)
- NYS EFC, Environmental Facilities Corporation (New York State)
- Essendon Football Club, an Australian rules football club
- European Film College, a Danish film college with students from all over the world
- European Foundation Centre, a European association of independent funders
- Evangelical Fellowship of Canada, a Canadian church association
- Everton F.C., an English professional football (soccer) club.
- Expect Further Clearance, an aviation term referring to a time by which you should receive additional instructions when assigned a holding pattern
- Expected Family Contribution, a concept related to college student financial aid in the United States
- Explosive Force Crew a street-fitnnes Bulgarian crew.