Dragonfire can refer to:
- Dragonfire (Doctor Who), a 1987 serial in the science fiction television series Doctor Who
- Dragonfire (video game), a video game released by Imagic
- Dragonfire (novel) an Andrew Kaplan spy thriller about a CIA agent trying to prevent another Southeast war
- Alternate title of Tagget, a 1991 spy film/thriller
- Dragonfire II: The Dungeonmaster's Assistant a 1985 computer program for managing tabletop role-playing games
Dragon's Fire is the 18th novel in the Dragonriders of Pern series.