Plot
While searching for an elixir of life, Dr. Henry Jekyll begins using female hormones taken from fresh cadavers supplied by Burke and Hare, reasoning that these hormones will help him to extend his life since women traditionally live for longer than men. These have the effect of not only altering his character (for the worse) but also of changing his gender, transforming him into a beautiful but evil woman. To explain the sudden appearance of his female half around the house, he calls himself Mrs. Hyde, saying she is Jekyll's widowed sister. Dr. Jekyll soon falls in love with Susan Spencer, the upstairs tenant, but Sister Hyde develops a lust for her brother.
Dr. Jekyll soon finds that his serum requires a regular supply of female hormones to maintain its effect, necessitating the killing of young girls. Burke and Hare supply his needs but their criminal activities are uncovered. Burke is lynched by a mob and Hare blinded. The doctor decides to take the matters into his own hands and commits the murders attributed to Jack the Ripper. Dr. Jekyll abhors this, but Sister Hyde relishes the killings as she begins to take control, even killing Jekyll's friend Professor Robertson when he attempts to question Hyde about the murders.
As the two personalities begin to struggle for dominance, Dr. Jekyll only just manages to thwart Sister Hyde's attempt to kill Susan. He then commits one last murder to find a way to stabilize his condition, but he is interrupted by the police after a comment by Hare leads them to realize the similarity between Jekyll's earlier experiments on cadavers and the Ripper murders. As Dr. Jekyll tries to escape by climbing along the outside of a building, he transforms into Sister Hyde, who, lacking his strength, falls to the ground, dying as a twisted amalgamation of male and female.
Read more about this topic: Dr. Jekyll And Sister Hyde
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