DEK can stand for several different things:
As an abbreviation, it is the initials of:
- David E. Kelley
- Donald Knuth
DEK is also an acronym for:
- German Evangelical Church (German: Deutsche Evangelische Kirche; 1933–1945)
- German Evangelical Church in Bohemia, Moravia and Silesia
- The DEK oncogene, a human gene
- Deutsche Extrakt Kaffee GmbH, a major European producer of soluble coffee
- Deutsche Einheitskurzschrift, a German stenography system