People
- David Lane (activist) (born c. 1955), American social conservative Christian political activist
- David Lane (cricketer) (born 1965), Montserratian cricketer
- David Lane (director), director of the film Thunderbirds are GO and various episodes of Gerry Anderson TV series
- David Lane (lawyer) (born 1954), American lawyer
- David Lane (musician) (born 1981), Australian musician with You Am I
- David Lane (politician) (1922–1998), British Conservative Party politician
- David Lane (white nationalist) (1938–2007), American white nationalist leader, author and convict
- David A. Lane (born 1945), professor of statistics and economics at the University of Modena and Reggio Emilia
- David C. Lane (born 1956), American professor of philosophy and critic of certain new religious movements
- David Ian (David Ian Lane, born 1961), English stage actor and theatre producer
- David J. Lane, Canadian astronomer
- David J. Lane (ambassador), United States Ambassador to the United Nations Agencies for Food and Agriculture
- Sir David Lane (oncologist) (born 1952), British oncologist
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