Darby may refer to:
- Darby (name), a given name and surname, including a list of people with the name, as well as those named D'Arby
Places:
- Darby River, Victoria, Australia
- Darby, Montana, a town
- Darby Township, Madison County, Ohio
- Darby Township, Pickaway County, Ohio
- Darby Township, Union County, Ohio
- Lake Darby, Ohio
- Darby, Pennsylvania, a borough
- Darby (SEPTA station)
- Darby Township, Delaware County, Pennsylvania
- Darby Creek (Pennsylvania)
Other uses:
- Hurricane Darby (disambiguation)
- USS Darby (DE-218), US Navy destroyer escort
- Camp Darby, U.S. military camp in Italy
- Darby, New Hampshire, a fictional town in a series of novels by Ernest Hebert
- Darby Bible, a translation of the Holy Bible