Cristóbal or Cristobal may refer to:
- Dominican Republic
- Cristóbal (municipality of the Independencia) province
- Panama
- Cristóbal, Colón
- Spain
- Cristóbal, Salamanca
- Christopher Columbus
- Cristóbal Colón, the Spanish rendition of Christopher Columbus' name
- Other
- Carmen Lelia Cristóbal, an Argentinian professor of botany
- Cristobal Huet, a French professional ice hockey goaltender
- Cristóbal Márquez Crespo, a Spanish football (soccer) player known as simply Cristóbal
- Cristobal (carbine), a Dominican-made automatic rifle
- Cristobal (horse), Thoroughbred racehorse
- Fort San Cristóbal, Puerto Rico
- Tropical Storm Cristobal (disambiguation), several tropical storms
- Marco Antonio Orozco, Chilean singer known as Cristóbal