Colo has several meanings:
- Colo (gorilla), a gorilla individual
- Colo (volcano) in Indonesia
- Colo, Iowa, a small city in the United States
- Colo, New South Wales, a town in Australia
- Colo River in Australia
- Colo, an alternate name for the Alemow (Citrus × macrophylla)
- Colo., an abbreviation for the U.S. state of Colorado
- Colo, a colloquial term for the French École Nationale de la France d'Outre-Mer
- Short for colocation centre