Clothier may refer to one of the following professions:
- Tailor – the most common modern usage
- Cloth merchant
- A cloth manufacturer – see cloth production
As a surname, Clothier may refer to one of the following individuals:
- Hurshul Clothier (1922–2006), American western swing band musician and bandleader
- Robert Clothier (1921–1999), Canadian stage and television actor
- Robert Clarkson Clothier (1885–1970), president of Rutgers University 1932–1951 and president of the New Jersey Constitutional Convention of 1947
- William Clothier (1881–1962), American tennis player
- William H. Clothier (1903–1996), American cinematographer
The Long Beach Clothiers were a baseball team in the Southern California Trolley League in 1910.