Safety
All of these acids are unusually strong for organic acids, and should generally be treated with similar care as for strong mineral acids like hydrochloric acid. Even neutral salts however, tend to be significantly toxic, because the ions interfere in biological processes (such as the citric acid cycle) that normally process plain acetate ions. Interestingly, the chloroacetate anion is the most toxic, with a rat, oral LD50 of about 0.5 g/kg.
Read more about this topic: Chloroacetic Acids
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