In Biomaterials Testing, a cell culture assay is any method which is used to assess the cytotoxicity of a material. This refers to the in vitro assessment of material to determine whether it releases toxic chemicals in sufficient quantities to kill cells either directly or indirectly through the inhibition of cell metabolic pathways. Cell culture evaluations are the precursor to whole animal studies and are a way to determine if significant cytotoxicity exists for the given material. Cell culture assays are standardized by ASTM, ISO, and BSI (British Standards Institution.)
Famous quotes containing the words cell, culture and/or assays:
“each in the cell of himself is almost convinced of his freedom,”
—W.H. (Wystan Hugh)
“Cynicism makes things worse than they are in that it makes permanent the current condition, leaving us with no hope of transcending it. Idealism refuses to confront reality as it is but overlays it with sentimentality. What cynicism and idealism share in common is an acceptance of reality as it is but with a bad conscience.”
—Richard Stivers, U.S. sociologist, educator. The Culture of Cynicism: American Morality in Decline, ch. 1, Blackwell (1994)
“Your bait of falsehood takes this carp of truth,
And thus do we of wisdom and of reach,
With windlasses and with assays of bias,
By indirections find directions out.”
—William Shakespeare (1564–1616)