In Biomaterials Testing, a cell culture assay is any method which is used to assess the cytotoxicity of a material. This refers to the in vitro assessment of material to determine whether it releases toxic chemicals in sufficient quantities to kill cells either directly or indirectly through the inhibition of cell metabolic pathways. Cell culture evaluations are the precursor to whole animal studies and are a way to determine if significant cytotoxicity exists for the given material. Cell culture assays are standardized by ASTM, ISO, and BSI (British Standards Institution.)
Famous quotes containing the words cell, culture and/or assays:
“Women have no wilderness in them,
They are provident instead,
Content in the tight hot cell of their hearts
To eat dusty bread.”
—Louise Bogan (1897–1970)
“One of the oddest features of western Christianized culture is its ready acceptance of the myth of the stable family and the happy marriage. We have been taught to accept the myth not as an heroic ideal, something good, brave, and nearly impossible to fulfil, but as the very fibre of normal life. Given most families and most marriages, the belief seems admirable but foolhardy.”
—Jonathan Raban (b. 1942)
“Your bait of falsehood takes this carp of truth,
And thus do we of wisdom and of reach,
With windlasses and with assays of bias,
By indirections find directions out.”
—William Shakespeare (1564–1616)