In Biomaterials Testing, a cell culture assay is any method which is used to assess the cytotoxicity of a material. This refers to the in vitro assessment of material to determine whether it releases toxic chemicals in sufficient quantities to kill cells either directly or indirectly through the inhibition of cell metabolic pathways. Cell culture evaluations are the precursor to whole animal studies and are a way to determine if significant cytotoxicity exists for the given material. Cell culture assays are standardized by ASTM, ISO, and BSI (British Standards Institution.)
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“Women have no wilderness in them,
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To eat dusty bread.”
—Louise Bogan (1897–1970)
“The second fundamental feature of culture is that all culture has an element of striving.”
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“Your bait of falsehood takes this carp of truth,
And thus do we of wisdom and of reach,
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By indirections find directions out.”
—William Shakespeare (1564–1616)