In Biomaterials Testing, a cell culture assay is any method which is used to assess the cytotoxicity of a material. This refers to the in vitro assessment of material to determine whether it releases toxic chemicals in sufficient quantities to kill cells either directly or indirectly through the inhibition of cell metabolic pathways. Cell culture evaluations are the precursor to whole animal studies and are a way to determine if significant cytotoxicity exists for the given material. Cell culture assays are standardized by ASTM, ISO, and BSI (British Standards Institution.)
Famous quotes containing the words cell, culture and/or assays:
“There’s not one part of his physical being that’s like that of human beings. From his warped brain down to the tiniest argumentative cell of his huge carcass, he’s unearthly.”
—Willis Cooper. Rowland V. Lee. Wolf von Frankenstein (Basil Rathbone)
“Nobody seriously questions the principle that it is the function of mass culture to maintain public morale, and certainly nobody in the mass audience objects to having his morale maintained.”
—Robert Warshow (1917–1955)
“Your bait of falsehood takes this carp of truth,
And thus do we of wisdom and of reach,
With windlasses and with assays of bias,
By indirections find directions out.”
—William Shakespeare (1564–1616)