In Biomaterials Testing, a cell culture assay is any method which is used to assess the cytotoxicity of a material. This refers to the in vitro assessment of material to determine whether it releases toxic chemicals in sufficient quantities to kill cells either directly or indirectly through the inhibition of cell metabolic pathways. Cell culture evaluations are the precursor to whole animal studies and are a way to determine if significant cytotoxicity exists for the given material. Cell culture assays are standardized by ASTM, ISO, and BSI (British Standards Institution.)
Famous quotes containing the words cell, culture and/or assays:
“Why inspire in us a horror of our being?... To look upon the universe as a prison cell and all men as criminals about to be executed is the idea of a fanatic.”
—Voltaire [François Marie Arouet] (1694–1778)
“The genius of American culture and its integrity comes from fidelity to the light. Plain as day, we say. Happy as the day is long. Early to bed, early to rise. American virtues are daylight virtues: honesty, integrity, plain speech. We say yes when we mean yes and no when we mean no, and all else comes from the evil one. America presumes innocence and even the right to happiness.”
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“Your bait of falsehood takes this carp of truth,
And thus do we of wisdom and of reach,
With windlasses and with assays of bias,
By indirections find directions out.”
—William Shakespeare (1564–1616)