CDB can refer to:
In music:
- CDB (band), an Australian band
- Charlie Daniels Band, the band of American musician Charlie Daniels
- Chris de Burgh, a British-Irish singer-songwriter
In organizations:
- Caribbean Development Bank, an international financial institution
- China Development Bank, a Chinese financial institution
- Cyprus Development Bank, a financial institution in Cyprus
- Community development bank, a type of bank in the United States
- Central Databank, an Irish online backup service provider
- Cleveland Daily Banner, a Tennessee newspaper
- Congested Districts Board (disambiguation), in particular
- Congested Districts Board for Ireland
- Congested Districts Board (Scotland)
- Council of Docked Breeds, a dog-breeding related non-profit organization
In science and technology:
- Constant Data Base, see cdb (software), a database engine
- Command Data Buffer, a data transfer method
- Common Data Bus for the Tomasulo algorithm used for scheduling computer instructions
- SCSI CDB (Command Descriptor Block), used when issuing commands to SCSI devices
- Microsoft Console Debugger, part of Debugging Tools for Windows
In other:
- CDB!, a children's book by William Steig
- CDB-4124, a biochemical agent
- Cold Bay Airport, an airport that has IATA airport code CDB
- Crim Dell bridge at the College of William & Mary