Treatment
ATP is required to reuptake calcium into the sarcomere's sarcoplasmic reticulum (SR). When a muscle is relaxed, the myosin heads are returned to their "high energy" position, ready and waiting for a binding site on the actin filament to become available. Because there is no ATP available, previously released calcium ions cannot return to the SR. These leftover calcium ions move around inside the sarcomere and may eventually find their way to a binding site on the thin filament's regulatory protein. Since the myosin head is already ready to bind, no additional ATP expenditure is required and the sarcomere contracts.
When this process occurs on a larger scale, the stiffening associated with rigor mortis can occur. It mainly occurs during high ATP use. Sometimes, cadaveric spasms can be associated with erotic asphyxiation resulting in death.
Read more about this topic: Cadaveric Spasm
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