Busia may refer to the following:
- Places
- Busia District, Kenya
- Busia District, Uganda
- Busia, Kenya, a Kenyan town on the border with Uganda
- Busia, Uganda, a Ugandan town on the border with Kenya
- People
- Kofi Abrefa Busia, Prime Minister of Ghana 1969–1972
- Akosua Busia, US based, Ghanaian born actress