Physiology
The process of filtration of the blood in the Bowman's capsule is ultrafiltration (or glomerular filtration), and the normal rate of filtration is 125 ml/min, equivalent to 80 times the daily blood volume.
Any proteins under roughly 30 kilodaltons can pass freely through the membrane, although there is some extra hindrance for negatively charged molecules due to the negative charge of the basement membrane and the podocytes.
Any small molecules such as water, glucose, salt (NaCl), amino acids, and urea pass freely into Bowman's space, but cells, platelets and large proteins do not.
As a result, the filtrate leaving the Bowman's capsule is very similar to blood plasma in composition as it passes into the proximal convoluted tubule.
Read more about this topic: Bowman's Capsule
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