Modes of Resistance
By definition, all β-lactam antibiotics have a β-lactam ring in their structure. The effectiveness of these antibiotics relies on their ability to reach the PBP intact and their ability to bind to the PBP. Hence, there are two main modes of bacterial resistance to β-lactams:
Read more about this topic: Beta-lactam Antibiotic
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“Heaven is large, and affords space for all modes of love and fortitude. Why should we be busybodies and superserviceable?”
—Ralph Waldo Emerson (18031882)
“Without any extraordinary effort of genius, I have discovered that nature was the same three thousand years ago as at present; that men were but men then as well as now; that modes and customs vary often, but that human nature is always the same. And I can no more suppose, that men were better, braver, or wiser, fifteen hundred or three thousand years ago, than I can suppose that the animals or vegetables were better than they are now.”
—Philip Dormer Stanhope, 4th Earl Chesterfield (16941773)
“He made no resistance whatever, and was stabbed in the back.... I must not dwell upon the fearful repast.... Words have no power to impress the mind with the exquisite horror of their reality.”
—Edgar Allan Poe (18091849)