Astin is a family name.
People:
- Alexander Astin - Professor at the University of California, Los Angeles
- Alexandra Astin - American actress, daughter of actor Sean Astin
- Allen V. Astin - Director of the National Institute of Standards and Technology 1951–1969
- Christine Astin - Wife of Sean Astin
- Edwin R. Astin - Author of "The Wicked Bible" (2001), referring to a Bible published in 1631
- Foulque D'Astin - Bishop of Lisieux 1250–1267
- John Astin - American actor
- Mackenzie Astin - American actor, son of Patty Duke and John Astin
- Patty Duke Astin - American actress, wife of John Astin
- Sean Astin - American film actor, director, and producer, son of Patty Duke Astin
- Skylar Astin - American actor
- Queen Vashti - first wife of King Ahasuerus in the Book of Esther.
Fictional people:
- Jan Rek ter'Astin - A character in the fictional Liaden universe
- Dr. Robert Astin - A fictional doctor in the United States television series Quincy
Other:
- ASTIN - A section of the International Actuarial Association, an acronym for "Actuarial STudies In Non-life insurance"
- ASTIN Bulletin - An international scientific journal for actuarial mathematics
- Astin Weight - Piano manufacturer
- Allen V. Astin Measurement Science Award
- R. Q. Astin House - Building in Brazos County, Texas, USA
- J. P. Astin House - Building in Jones County, Texas, USA