Russian Anthrax Vaccines
Anthrax vaccines were developed in the Soviet Union in the 1930s and available for use in humans by 1940. A live attenuated, unencapsulated spore vaccine became widely used for humans. It was given either by scarification or subcutaneously and its developers claimed that it was reasonably well tolerated and showed some degree of protective efficacy against cutaneous anthrax in clinical field trials. The efficacy of the live Russian vaccine was reported to have been greater than that of either of the killed British or US anthrax vaccines (AVP and AVA, respectively) during the 1970s and '80s. Today both Russia and China use live attenuated strains for their human vaccines. These vaccines may be given by aerosol, scarification, or subcutaneous injection. A Georgian/Russian live anthrax spore vaccine (called STI) was based on spores from the Stern strain of B. anthracis. It was given in a two-dose schedule, but serious side-effects restricted its use to healthy adults. It was reportedly manufactured at the George Eliava Institute of Bacteriophage, Microbiology and Virology in Tbilisi, Georgia, until 1991.
Read more about this topic: Anthrax Vaccines
Famous quotes containing the word russian:
“Who are we? And for what are we going to fight? Are we the titled slaves of George the Third? The military conscripts of Napoleon the Great? Or the frozen peasants of the Russian Czar? No—we are the free born sons of America; the citizens of the only republic now existing in the world; and the only people on earth who possess rights, liberties, and property which they dare call their own.”
—Andrew Jackson (1767–1845)