Anaplasma Phagocytophilum - Role in Human Disease

Role in Human Disease

Anaplasma phagocytophilum causes human granulocytic anaplasmosis. This disease was first identified in 1990, although this pathogen was known to cause veterinary disease since 1932. Since 1990, incidence of this disease has increased, and it is now recognized in Europe. This disease was first identified due to a Wisconsin patient who died with a severe febrile illness two weeks after a tick bite. During the last stage of the infection, a group of small bacteria were seen within the neutrophils in the blood. Other symptoms include fever, headache, absence of skin rash, leucopenia, thromboctytopenia and mild injury to the liver.

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