Negative
"Negative" acute-phase proteins decrease in inflammation. Examples include albumin, transferrin, transthyretin, retinol-binding protein, antithrombin, transcortin. The decrease of such proteins may be used as markers of inflammation. The physiological role of decreased synthesis of such proteins is generally to save amino acids for producing "positive" acute-phase proteins more efficiently. Theoretically, a decrease in transferrin could additionally be decreased by an upregulation of transferrin receptors, but the latter does not appear to change with inflammation.
Read more about this topic: Acute-phase Protein
Famous quotes containing the word negative:
“Isolation in creative work is an onerous thing. Better to have negative criticism than nothing at all.”
—Anton Pavlovich Chekhov (1860–1904)
“Most literature on the culture of adolescence focuses on peer pressure as a negative force. Warnings about the “wrong crowd” read like tornado alerts in parent manuals. . . . It is a relative term that means different things in different places. In Fort Wayne, for example, the wrong crowd meant hanging out with liberal Democrats. In Connecticut, it meant kids who weren’t planning to get a Ph.D. from Yale.”
—Mary Kay Blakely (20th century)
“The negative always wins at last, but I like it none the better for that.”
—Mason Cooley (b. 1927)