In biology the active site is part of an enzyme where substrates bind and undergo a chemical reaction. The majority of enzymes are proteins but RNA enzymes called ribozymes also exist. The active site of an enzyme is usually found in a cleft or pocket that is lined by amino acid residues (or nucleotides in ribozymes) that participate in recognition of the substrate. Residues that directly participate in the catalytic reaction mechanism are called active site residues.
Read more about Active Site: Binding Mechanism, Chemistry
Famous quotes containing the words active and/or site:
“In this lucid and flexible pattern only one thing remained always stationary, but this fallacy went unnoticed by Martha. The blind spot was the victim. The victim showed no signs of life before being deprived of it. If anything, the corpse which had to be moved and handled before burial seemed more active than its biological predecessor.”
—Vladimir Nabokov (1899–1977)
“It’s given new meaning to me of the scientific term black hole.”
—Don Logan, U.S. businessman, president and chief executive of Time Inc. His response when asked how much his company had spent in the last year to develop Pathfinder, Time Inc.’S site on the World Wide Web. Quoted in New York Times, p. D7 (November 13, 1995)