4EGI-1 is a synthetic, biological molecule, which has been found to interfere with the growth of certain types of cancer cells. Its mechanism of action interrupts the binding of cellular initiation factor proteins involved in the translation of transcribed mRNA at the ribosome. The inhibition of these initiation factors prevents the initiation and translation of many proteins whose functions are essential to the rapid growth and proliferation of cancer cells.
Read more about 4EGI-1: Reaction Mechanism, Binding Site Specifics and Effects of Use, CAP Dependent Vs. Initiation Factor Independent Translation, The Techniques of Discovery, The Medical Potential of 4EGI-1