Scope
IBX is also available as silica gel or polystyrene bound IBX. In many application IBX acid is replaced by Dess-Martin periodinane which is more soluble in common organic solvents. A sample reaction is an IBX oxidation used in the total synthesis of eicosanoid:
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In 2001, K. C. Nicolaou and co-workers published a series of papers in the Journal of the American Chemical Society demonstrating, among other transformations, the use of IBX to oxidize benzylic carbons to conjugated aromatic carbonyl compounds.
Read more about this topic: 2-Iodoxybenzoic Acid
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