1-phosphofructokinase
In enzymology,1-phosphofructokinase (PFK1) (EC 2.7.1.56) is an enzyme that catalyzes the chemical reaction
- ATP + D-fructose 1-phosphate → ADP + D-fructose 1,6-bisphosphate
Thus, the two substrates of this enzyme are ATP and D-fructose 1-phosphate, whereas its two products are ADP and D-fructose 1,6-bisphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-fructose-phosphate 6-phosphotransferase. Other names in common use include fructose-1-phosphate kinase, 1-phosphofructokinase (phosphorylating), D-fructose-1-phosphate kinase, fructose 1-phosphate kinase, and 1-phosphofructokinase. This enzyme participates in fructose and mannose metabolism.
Read more about 1-phosphofructokinase: Structure, Function, Clinical Significance