WOS may refer to:
- Web of Science, an online academic database
- Web operating system
- Wilson Ornithological Society
- Wizards of OS, a computing group
- World of Spectrum, a website dedicated to the 1980s ZX Spectrum home computer
- World of Springfield, a series of action figures based on the TV series The Simpsons
- Well of Souls, a natural cave in Jerusalem
- WhatsOnStage.com, which organises the Theatregoers' Choice Awards