WDFM may refer to:
- WDFM (FM), a radio station (98.1 FM) licensed to Defiance, Ohio, United States
- WDFM-LP, a low-power television station (channel 26) licensed to Defiance, Ohio, United States
- WPSU (FM), a radio station (91.5 FM) licensed to State College, Pennsylvania, United States, which used the call sign WDFM until August 1984