- Vernon Secondary School, a high school in Vernon, B.C.
- Valley Stream South High School in Valley Stream, New York
- Vaughan Secondary School, a public highschool located in Thornhill, Ontario operated by the York Region District School Board
- Voluntary Sports Societies of the USSR
- VUE Support Services, Pearson VUE's support service
- Veronis Suhler Stevenson, a private equity firm operating in the media and communications sector
- VSS Catholic Communications A catholic Radio station in Nebraska. It serves the Omaha, Lincoln, Norfolk, Grand Island, as well as the western Iowa area.
- Vision Sciences Society, an organization of researchers investigating the visual system
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