Other
- Andrew Velasquez (born 1969), American civil servant
- Baldemar Velasquez (born 1947), president of the Farm Labor Organizing Committee, AFL-CIO
- Daisy Velasquez, American activist
- Diego Velázquez de Cuéllar, Spanish conquistador leader of the conquest of Cuba
- Diego Velázquez Tlacotzin, puppet ruler of the Aztec Empire (1525-1526)
- Fidel Velázquez Sánchez, 20th-century Mexican union leader
- José Velásquez (explorer) (1717–1785), Spanish explorer
- José Velásquez Bórquez (1833–1897), Chilean general
- María Sofía Velásquez (born 1971), Panamanian beauty pageant winner
- Lieutenant Marta Louise Velasquez, a protagonist in "Traffic Department 2192"
- Ronny Velásquez (born 1951), Venezuelan anthropologist
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