Fictional Characters
- Alyx Vance, in the video game Half-Life 2
- Bagger Vance, in the movie Legend of Bagger Vance
- Bob Vance, a character from the U.S. version of The Office
- Dr. Eli Vance, in the video game Half-Life 2
- Lance Vance and Victor Vance, from the video game Grand Theft Auto: Vice City
- Leon Vance, director of NCIS in the television show NCIS
- Mary Vance, an orphan from L. M. Montgomery's Rainbow Valley
- Nell Vance, in the movie The Haunting
- Philo Vance, detective in several novels by S. S. Van Dine
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