Type III Hypersensitivity - Examples

Examples

Some clinical examples:

Disease Target antigen Main effects
Systemic lupus erythematosus Nuclear antigens
  • Nephritis
  • Skin lesions
  • Arthritis
Post-streptococcal glomerulonephritis Streptococcal cell wall antigens
  • Nephritis
Polyarteritis nodosa Hepatitis B virus surface antigen
  • Systemic vasculitis
Reactive arthritis Several bacterial antigens
  • Acute arthritis
Serum sickness Various
  • Arthritis
  • Vasculitis
  • Nephritis
Arthus reaction Various
  • Cutaneous vasculitis
Farmer's Lung Inhaled antigens (often mould or hay dust)
  • Alveolar inflammation
Henoch–Schönlein purpura Unknown, likely respiratory pathogen
  • Purpura
  • Glomerulonephritis
Unless else specified in boxes, then ref is:

Other examples are:

  • Subacute bacterial endocarditis
  • Symptoms of malaria

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