Turn (biochemistry) - Definition

Definition

According to the most common definition, a turn is a structural motif where the Cα atoms of two residues separated by few (usually 1 to 5) peptide bonds are in close approach (< 7 Å), while the corresponding residues do not form a regular secondary structure element such as an alpha helix or beta sheet. Contrary to helices, the backbone dihedral angles are not (roughly) constant for all the residues in the turn.

Although the close approach of the two terminal Cα atoms is usually correlated with the forming of one or two hydrogen bonds between the corresponding residues, such hydrogen bond is not strictly required in the definition of the turn. That said, in most cases the H-bonding and Cα-distance definitions are equivalent.

Read more about this topic:  Turn (biochemistry)

Famous quotes containing the word definition:

    Although there is no universal agreement as to a definition of life, its biological manifestations are generally considered to be organization, metabolism, growth, irritability, adaptation, and reproduction.
    The Columbia Encyclopedia, Fifth Edition, the first sentence of the article on “life” (based on wording in the First Edition, 1935)

    The man who knows governments most completely is he who troubles himself least about a definition which shall give their essence. Enjoying an intimate acquaintance with all their particularities in turn, he would naturally regard an abstract conception in which these were unified as a thing more misleading than enlightening.
    William James (1842–1910)

    ... if, as women, we accept a philosophy of history that asserts that women are by definition assimilated into the male universal, that we can understand our past through a male lens—if we are unaware that women even have a history—we live our lives similarly unanchored, drifting in response to a veering wind of myth and bias.
    Adrienne Rich (b. 1929)