Sources of Inaccuracy
The high dose hook effect is an artefact of tumor marker immunoassay kits, that causes the reported quantity of tumor marker to be incorrectly low when the quantity is high. An undetected hook effect may cause delayed recognition of a tumor. The hook effect can be detected by analyzing serial dilutions. The hook effect is absent if the reported quantities of tumor marker in a serial dilution are proportional to the dilution.
Read more about this topic: Tumor Markers
Famous quotes containing the words sources of, sources and/or inaccuracy:
“No drug, not even alcohol, causes the fundamental ills of society. If we’re looking for the sources of our troubles, we shouldn’t test people for drugs, we should test them for stupidity, ignorance, greed and love of power.”
—P.J. (Patrick Jake)
“I count him a great man who inhabits a higher sphere of thought, into which other men rise with labor and difficulty; he has but to open his eyes to see things in a true light, and in large relations; whilst they must make painful corrections, and keep a vigilant eye on many sources of error.”
—Ralph Waldo Emerson (1803–1882)
“Truth is that concordance of an abstract statement with the ideal limit towards which endless investigation would tend to bring scientific belief, which concordance the abstract statement may possess by virtue of the confession of its inaccuracy and one-sidedness, and this confession is an essential ingredient of truth.”
—Charles Sanders Peirce (1839–1914)