People
- Allen Tough (b.1936), Canadian academic
- Dave Tough (1907–48), jazz drummer
- The Krankies, Ian and Janette Tough
- Kathy Tough, (b.1969) Canadian volleyball player
- Kelly Tough (b.1967), Canadian model and actress
- Paul Tough, Canadian writer
- Jim Barry, aka "Tough Barry", (c.1891–1967), Cork hurling coach
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