TLR 5

TLR 5

Identifiers Symbols TLR5; SLEB1; TIL3 External IDs OMIM: 603031 MGI: 1858171 HomoloGene: 20698 GeneCards: TLR5 Gene

Gene Ontology
Molecular function	• transmembrane signaling receptor activity • interleukin-1 receptor binding
Cellular component	• plasma membrane • integral to membrane
Biological process	• toll-like receptor signaling pathway • MyD88-dependent toll-like receptor signaling pathway • inflammatory response • positive regulation of interleukin-8 production • positive regulation of toll-like receptor signaling pathway • toll-like receptor 5 signaling pathway • toll-like receptor 10 signaling pathway • defense response to bacterium • innate immune response • regulation of cytokine secretion • cellular response to mechanical stimulus
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7100 53791 Ensembl ENSG00000187554 ENSMUSG00000079164 UniProt O60602 Q9JLF7 RefSeq (mRNA) NM_003268 NM_016928 RefSeq (protein) NP_003259 NP_058624 Location (UCSC) Chr 1:
223.28 – 223.32 Mb Chr 1:
182.95 – 182.98 Mb PubMed search

Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene.