Modified Analogs of Thymidine
Iododeoxyuridine is a radiosensitizer and increases the amount of DNA damage received from ionizing radiation.
Azidothymidine (AZT) - used in the treatment of HIV infection. AZT inhibits the process of reverse transcription, a critical step in the viral life cycle.
Tritiated thymidine is commonly used in cell proliferation assays. The thymidine is incorporated into dividing cells and the level of this incorporation, measured using a liquid scintillation counter, is proportional to the amount of cell proliferation.
Bromodeoxyuridine (BrdU) is another thymidine analog that is often used for the detection of proliferating cells in living tissues.
Edoxudine is an antiviral drug.
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